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1

Usefulness of Physical Maneuvers for Prevention of Vasovagal Syncope

Kim, Kye Hun, Cho, Jeong Gwan, Lee, Kyung Ok, Seo, Tae Jin, Shon, Chang Young, Lim, Sang Yup, Yun, Kyung Ho, Sohn, Il Suk, Hong, Young Joon, Park, Hyung Wook, Kim, Ju Han, Kim, Weon, Ahn, Young Keun,

Journal:

Circulation Journal

Year:

2005

Language:

english

File:

PDF, 413 KB

english, 2005

2

A 1.8-V 700-mb/s/pin 512-mb DDR-II SDRAM with on-die termination and off-chip driver calibration

Changsik Yoo, Kye-Hyun Kyung, Kyunam Lim, Hi-Choon Lee, Joon-Wan Chai, Nak-Won Heo, Dong-Jin Lee, Chang-Hyun Kim

Journal:

IEEE Journal of Solid-State Circuits

Year:

2004

Language:

english

File:

PDF, 972 KB

english, 2004

3

Nimodipine and Steroid Combination Therapy for Idiopathic Sudden Sensorineural Hearing Loss

Han, Jae Joon, Jung, Jae Yeup, Park, Kye Hoon, Lee, Ho Yun, Lee, Byung Don, Choi, Seong Jun, Lee, Chi Kyou

Journal:

Otology & Neurotology

Year:

2020

File:

PDF, 361 KB

2020

4

Clinicopathologic Efficacy of Copper Bromide Plus/Yellow Laser (578 nm with 511 nm) for Treatment of Melasma in Asian Patients

HYE IN LEE, YUN YOUNG LIM, BEOM JOON KIM, MYEUNG NAM KIM, HYE JUNG MIN, JUNG HEE HWANG, KYE YONG SONG

Journal:

Dermatologic Surgery

Year:

2010

Language:

english

File:

PDF, 1.65 MB

english, 2010

5

Fractional Photothermolysis Laser Treatment of Male Pattern Hair Loss

WON-SERK KIM, HYE IN LEE, JIN WOONG LEE, YUN YOUNG LIM, SEUNG JAE LEE, BEOM JOON KIM, MYEUNG NAM KIM, KYE YONG SONG, WON SERK PARK

Journal:

Dermatologic Surgery

Year:

2011

Language:

english

File:

PDF, 3.25 MB

english, 2011

6

The complex extracellular biology of Streptomyces

Keith F. Chater, Sandor Biró, Kye Joon Lee, Tracy Palmer, Hildgund Schrempf

Journal:

FEMS Microbiology Reviews

Year:

2010

Language:

english

File:

PDF, 562 KB

english, 2010

7

BRCA1 and BRCA2 germline mutations in Korean breast cancer patients at high risk of carrying mutations

Sei Hyun Ahn, Byung Ho Son, Kyung-Sik Yoon, Dong-Young Noh, Wonshik Han, Sung-Won Kim, Eun Sook Lee, Hai-Lin Park, Young Joon Hong, Jae Jin Choi, Seo Yun Moon, Mi Jeong Kim, Kye Hyun Kim, Beom Seok Kw

Journal:

Year:

2007

Language:

english

File:

PDF, 97 KB

english, 2007

8

Kinetic study on the production and degradation of leupeptin in streptomyces exfoliatus smf13

In Seop Kim, Kye Joon Lee

Journal:

Journal of Biotechnology

Year:

1995

Language:

english

File:

PDF, 917 KB

english, 1995

9

Intense focused ultrasound for facial tightening: Histologic changes in 11 Patients

Suh, Dong Hye, So, Byoung Joon, Lee, Sang Jun, Song, Kye-Yong, Ryu, Hwa Jung

Journal:

Journal of Cosmetic and Laser Therapy

Year:

2015

Language:

english

File:

PDF, 342 KB

english, 2015

10

Long-Term Clinical Outcomes of Platelet Glycoprotein IIb/IIIa Inhibitor Combined With Low Molecular Weight Heparin in Patients With Acute Coronary Syndrome

Kim, Ju Han, Jeong, Myung Ho, Rhew, Jay Young, Lim, Ji Hyun, Yun, Kyung Ho, Kim, Kye Hun, Kang, Dong Koo, Hong, Seo Na, Lim, Sang Yup, Lee, Sang Hyun, Lee, Yeon Sang, Hong, Young Joon, Park, Hyung Woo

Journal:

Circulation Journal

Year:

2005

Language:

english

File:

PDF, 155 KB

english, 2005

11

Myocardial Protective Effects of Nicorandil During Percutaneous Coronary Intervention in Patients With Unstable Angina

Kim, Ju Han, Jeong, Myung Ho, Yun, Kyung Ho, Kim, Kye Hun, Kang, Dong Koo, Hong, Seo Na, Lim, Sang Yup, Lee, Sang Hyun, Lee, Yun Sang, Hong, Young Joon, Park, Hyung Wook, Kim, Weon, Ahn, Young Keun, C

Journal:

Circulation Journal

Year:

2005

Language:

english

File:

PDF, 206 KB

english, 2005

12

Elevated Preprocedural High-Sensitivity C-Reactive Protein Levels are Associated With Neointimal Hyperplasia and Restenosis Development After Successful Coronary Artery Stenting

Hong, Young Joon, Jeong, Myung Ho, Lim, Sang Yup, Lee, Sang Rok, Kim, Kye Hun, Sohn, Il Suk, Park, Hyung Wook, Kim, Ju Han, Kim, Weon, Ahn, Youngkeun, Cho, Jeong Gwan, Park, Jong Chun, Kang, Jung Chae

Journal:

Circulation Journal

Year:

2005

Language:

english

File:

PDF, 258 KB

english, 2005

13

Control of type O foot-and-mouth disease by vaccination in Korea, 2014–2015

Park, Jong-Hyeon, Tark, Dongseob, Lee, Kwang-Nyeong, Chun, Ji-Eun, Lee, Hyang-Sim, Ko, Young-Joon, Kye, Soo-Jeong, Kim, Yong-Joo, Oem, Jae-Ku, Ryoo, Soyoon, Lim, Sung-Bin, Lee, Seo-Yong, Choi, Joo-Hyu

Journal:

Journal of Veterinary Science

Year:

2018

Language:

english

File:

PDF, 1.10 MB

english, 2018

14

The Clinical Effects of Nicorandil during Percutaneous Coronary Intervention in Patients with Unstable Angina

Kim, Ju Han, Jeong, Myung Ho, Lim, Sang Yup, Lee, Sang Hyun, Lee, Yun Sang, Yoon, Kyung Ho, Kang, Dong Goo, Kim, Kye Hun, Hong, Young Joon, Park, Hyung Wook, Park, Ok Young, Kim, Weon, Ahn, Young Keun

Journal:

Korean Circulation Journal

Year:

2005

Language:

english

File:

PDF, 481 KB

english, 2005

15

Kinetics of alcohol fermentation at high yeast levels

E. J. del Rosario, Kye Joon Lee, P. L. Rogers

Journal:

Biotechnology and Bioengineering

Year:

1979

Language:

english

File:

PDF, 231 KB

english, 1979

16

ChemInform Abstract: Practical Synthesis of (S)-7-(2-Isopropylamino)ethylcamptothecin Hydrochloride, Potent Topoisomerase I Inhibitor.

Soon Kil Ahn, Nam Song Choi, Byeong Seon Jeong, Kye Kwang Kim, Duck Jin Journ, Joon Kyum Kim, Sang Joon Lee, Jung Woo Kim, Chung Il Hong, Sang-sup Jew

Journal:

Year:

2001

File:

PDF, 29 KB

2001

17

Practical synthesis of (S)-7-(2-isopropylamino)ethylcamptothecin hydrochloride, potent topoisomerase I inhibitor

Soon Kil Ahn, Nam Song Choi, Byeong Seon Jeong, Kye Kwang Kim, Duck Jin Journ, Joon Kyum Kim, Sang Joon Lee, Jung Woo Kim, Chung Hong II, Sang-Sup Jew

Journal:

Journal of Heterocyclic Chemistry

Year:

2000

File:

PDF, 210 KB

2000

18

Successful management of huge floating thrombus within aortic arch in a patient with old myocardial infarction

Hyun Ju Yoon, Myung Ho Jeong, Sang Ki Oho, In Seok Jeong, Byoung Hee Ahn, Chang Sung Kim, Min Goo Lee, Jum Suk Ko, Keun Ho Park, Doo Sun Sim, Nam Sik Yoon, Hyung Wook Park, Young Joon Hong, Kye Hun Ki

Journal:

Journal of Cardiology Cases

Year:

2010

Language:

english

File:

PDF, 447 KB

english, 2010

19

A case of asymptomatic giant coronary aneurysm with atrioventricular fistula

Hyun Ju Yoon, Myung Ho Jeong, Min Goo Lee, Jum Seok Ko, Keun Ho Park, Doo Sun Sim, Nam Sik Yoon, Kye Hun Kim, Hyung Wook Park, Young Joon Hong, Ju Han Kim, Youngkeun Ahn, Jeong Gwan Cho, Jong Chun Par

Journal:

Journal of Cardiology Cases

Year:

2010

Language:

english

File:

PDF, 232 KB

english, 2010

20

Ethanol production byZymomonas mobilis in continuous culture at high glucose concentrations

Kye Joon Lee, D. E. Tribe, P. L. Rogers

Journal:

Biotechnology Letters

Year:

1979

Language:

english

File:

PDF, 283 KB

english, 1979

21

Kinetics of alcohol production by zymomonas mobilis at high sugar concentrations

P. L. Rogers, Kye Joon Lee, D. E. Tribe

Journal:

Biotechnology Letters

Year:

1979

Language:

english

File:

PDF, 286 KB

english, 1979

22

Clavulanic acid biosynthesis and genetic manipulation for its overproduction

Ju Yeon Song, Susan E. Jensen, Kye Joon Lee

Journal:

Applied Microbiology and Biotechnology

Year:

2010

Language:

english

File:

PDF, 279 KB

english, 2010

23

Identification of an intermediate state as spermatogonial stem cells reprogram to multipotent cells

Hyung Joon Kim, Hyun Jung Lee, Jung Jin Lim, Ki Hoon Kwak, Jong Soo Kim, Ji Hoon Kim, Yong-Mahn Han, Kye-Seong Kim, Dong Ryul Lee

Journal:

Molecules and Cells

Year:

2010

Language:

english

File:

PDF, 1.40 MB

english, 2010

24

A gene located downstream of the clavulanic acid gene cluster inStreptomyces clavuligerusATCC 27064 encodes a putative response regulator that affects clavulanic acid production

Ju Yeon Song, Eun Sook Kim, Dae Wi Kim, Susan E. Jensen, Kye Joon Lee

Journal:

Journal of Industrial Microbiology & Biotechnology

Year:

2009

Language:

english

File:

PDF, 550 KB

english, 2009

25

The role of 64-slice multi-detector computed tomography in the detection of subclinical atherosclerosis of the coronary artery

Hae Chang Jeong, Youngkeun Ahn, Jum Suk Ko, Min Goo Lee, Doo Sun Sim, Keun Ho Park, Nam Sik Yoon, Hyun Ju Youn, Young Joon Hong, Kye Hun Kim, Hyung Wook Park, Ju Han Kim, Yun-Hyeon Kim, Myung Ho Jeong

Journal:

The International Journal of Cardiovascular Imaging

Year:

2010

Language:

english

File:

PDF, 187 KB

english, 2010

26

The relationship between glucuronide conjugate levels and hepatotoxicity after oral administration of valproic acid

Min Sun Lee, Young-Joo Lee, Bo Joon Kim, Kye Jung Shin, Bong Chul Chung, Du-Jong Baek, Byung Hwa Jung

Journal:

Archives of Pharmacal Research

Year:

2009

Language:

english

File:

PDF, 201 KB

english, 2009

27

Induction of connective tissue growth factor expression by sphingosylphosphorylcholine in cultured human skin fibroblasts

Ming Ji Zhu, Chang Deok Kim, Yoo Bin Kwon, Kyung-Chae Kye, Yuan Yao Chen, Woong-Hee Lee, Sangkeun Lee, Jong Soon Lim, Young-Joon Seo, Ki-Beom Suhr, Jang-Kyu Park, Jeung-Hoon Lee

Journal:

Experimental Dermatology

Year:

2005

Language:

english

File:

PDF, 740 KB

english, 2005

28

Involvement of urokinase-type plasminogen activator in sphingosylphosphorylcholine-induced angiogenesis

Yong-Jun Piao, Chang-Hi Lee, Ming Ji Zhu, Kyung-Chae Kye, Jin-Man Kim, Young-Joon Seo, Ki-Beom Suhr, Jang-Kyu Park, Chang Deok Kim, Jeung-Hoon Lee

Journal:

Experimental Dermatology

Year:

2005

Language:

english

File:

PDF, 897 KB

english, 2005

29

Structural basis for the extended substrate spectrum of CMY-10, a plasmid-encoded class C β-lactamase

Jae Young Kim, Ha Il Jung, Young Jun An, Jung Hun Lee, So Jung Kim, Seok Hoon Jeong, Kye Joon Lee, Pann-Ghill Suh, Heung-Soo Lee, Sang Hee Lee, Sun-Shin Cha

Journal:

Molecular Microbiology

Year:

2006

Language:

english

File:

PDF, 3.02 MB

english, 2006

30

Complex extracellular interactions of proteases and a protease inhibitor influence multicellular development of Streptomyces coelicolor

Dae Wi Kim, Andy Hesketh, Eun Sook Kim, Ju Yeon Song, Dae Hoon Lee, In Seop Kim, Keith F. Chater, Kye Joon Lee

Journal:

Molecular Microbiology

Year:

2008

Language:

english

File:

PDF, 608 KB

english, 2008

31

Central trichoptilosis with onycholysis

Myung Im, Kyung-Chae Kye, Young-Joon Seo, Jeung-Hoon Lee, Jang-Kyu Park

Journal:

International Journal of Dermatology

Year:

2006

Language:

english

File:

PDF, 107 KB

english, 2006

32

Actinorhodin and undecylprodigiosin production in wild-type and relA mutant strains of Streptomyces coelicolor A3(2) grown in continuous culture

Sung Gyun Kang, Wook Jin, Mervyn Bibb, Kye Joon Lee

Journal:

FEMS Microbiology Letters

Year:

1998

Language:

english

File:

PDF, 169 KB

english, 1998

33

Restriction fragment length dimorphism–PCR method for the detection of extended-spectrum β-lactamases unrelated to TEM- and SHV-types

Sang Hee Lee, Jae Young Kim, Sang Heum Shin, Seok Ki Lee, Myung Min Choi, In Yong Lee, Young Bae Kim, Jung Youn Cho, Wook Jin, Kye Joon Lee

Journal:

FEMS Microbiology Letters

Year:

2001

Language:

english

File:

PDF, 218 KB

english, 2001

34

10.1038/nsb1001-848

Lim, Daniel, Park, Hyeon Ung, De Castro, Liza, Kang, Sung Gyun, Lee, Hyun Sook, Jensen, Susan, Lee, Kye Joon, Strynadka, Natalie C.J.

Journal:

Natural Structural Biology

Year:

2001

Language:

english

File:

PDF, 4.14 MB

english, 2001

35

Expression of Neutrophil Gelatinase-Associated Lipocalin in Skin Epidermis

Seo, Seong Jun, Ahn, Ji-Young, Hong, Chang-Kwun, Seo, Eun-Young, Kye, Kyung-Chae, Lee, Woong-Hee, Lee, Sang-Keun, Lim, Jong-Soon, Hahn, Myong-Joon, Kjeldsen, Lars

Journal:

The Journal of Investigative Dermatology

Year:

2005

Language:

english

File:

PDF, 136 KB

english, 2005

36

Preinterventional peak monocyte count and in-stent intimal hyperplasia after coronary stent implantation in human coronary arteries

Young Joon Hong, Myung Ho Jeong, Sang Yup Lim, Sang Rok Lee, Kye Hun Kim, Il Suk Sohn, Hyung Wookpark, Ju Han Kim, Weon Kim, Youngkeun Ahn, Jeong Gwan Cho, Jong Chun Park, Jung Chaee Kang

Journal:

Clinical Cardiology

Year:

2005

Language:

english

File:

PDF, 110 KB

english, 2005

37

Regulation of production of leupeptin, leupeptin-inactivating enzyme, and trypsin-like protease in Streptomyces exfoliatus SMF13

In Seop Kim, Kye Joon Lee

Journal:

Journal of Fermentation and Bioengineering

Year:

1995

Language:

english

File:

PDF, 808 KB

english, 1995

38

Prognostic significance of simvastatin therapy in patients with ischemic heart failure who underwent percutaneous coronary intervention for acute myocardial infarction

Young Joon Hong, Myung Ho Jeong, Dae Woo Hyun, Seung Ho Hur, Kwon Bae Kim, Weon Kim, Sang Yup Lim, Sang Hyun Lee, Seo Na Hong, Dong Goo Kang, Kyung Ho Yun, Kye Hun Kim, Yun Sang Lee, Hyung Wook Park,

Journal:

The American Journal of Cardiology

Year:

2005

Language:

english

File:

PDF, 129 KB

english, 2005

39

Relation of Soft Plaque and Elevated Preprocedural High-Sensitivity C-Reactive Protein Levels to Incidence of In-Stent Restenosis After Successful Coronary Artery Stenting

Young Joon Hong, Myung Ho Jeong, Sang Yup Lim, Sang Rok Lee, Seo Na Hong, Kye Hun Kim, Il Suk Sohn, Hyung Wook Park, Ju Han Kim, Weon Kim, Youngkeun Ahn, Jeong Gwan Cho, Jong Chun Park, Jung Chaee Kan

Journal:

The American Journal of Cardiology

Year:

2006

Language:

english

File:

PDF, 162 KB

english, 2006

40

Usefulness of Serum N-Terminal Pro–Brain Natriuretic Peptide to Predict In-Stent Restenosis in Patients With Preserved Left Ventricular Function and Normal Troponin I Levels

Seo Na Hong, Youngkeun Ahn, Nam Sik Yoon, Ki Hong Lee, Yong Sook Kim, Seon Ho Hwang, Sang Rok Lee, Kye Hun Kim, Hyung Wook Park, Young Joon Hong, Ju Han Kim, Myung Ho Jeong, Jeong Gwan Cho, Jong Chun

Journal:

The American Journal of Cardiology

Year:

2007

Language:

english

File:

PDF, 90 KB

english, 2007

41

Usefulness of Preprocedural N-Terminal Pro-Brain Natriuretic Peptide in Predicting Angiographic No-Reflow Phenomenon During Stent Implantation in Patients With ST-Segment Elevation Acute Myocardial Infarction

Seo Na Hong, Youngkeun Ahn, Sun Ho Hwang, Nam Sik Yoon, Sang Rok Lee, Jae Youn Moon, Kye Hun Kim, Young Joon Hong, Hyung Wook Park, Ju Han Kim, Myung Ho Jeong, Jeong Gwan Cho, Jong Chun Park, Jung Cha

Journal:

The American Journal of Cardiology

Year:

2007

Language:

english

File:

PDF, 105 KB

english, 2007

42

AS-27: Plaque Characteristics in Culprit Lesions in Diabetic Acute Coronary Syndrome Patients: Intravascular Ultrasound and Virtual Histology-Intravascular Ultrasound Analysis

Young Joon Hong, Myung Ho Jeong, Yun Ha Choi, Jum Suk Ko, Min Goo Lee, Won Yu Kang, Shin Eun Lee, Soo Hyun Kim, Keun Ho Park, Doo Sun Sim, Nam Sik Yoon, Hyun Ju Youn, Kye Hun Kim, Hyung Wook Park, Ju

Journal:

The American Journal of Cardiology

Year:

2009

Language:

english

File:

PDF, 30 KB

english, 2009

43

AS-103: Effect of Ramiprilat-Coated Stent in a Porcine Coronary Restenosis Model

Young Joon Hong, Myung Ho Jeong, Jung Ha Kim, Kyung Seob Lim, Jum Suk Ko, Min Goo Lee, Won Yu Kang, Shin Eun Lee, Soo Hyun Kim, Doo Sun Sim, Keun Ho Park, Nam Sik Yoon, Hyun Ju Youn, Kye Hun Kim, Hyun

Journal:

The American Journal of Cardiology

Year:

2009

Language:

english

File:

PDF, 37 KB

english, 2009

44

AS-102: Effects of Combined Therapy with Ezetimibe Plus Simvastatin after Drug-Eluting Stent Implantation in a Porcine Coronary Restenosis Model

Young Joon Hong, Myung Ho Jeong, Jung Ha Kim, Kyung Seob Lim, Jum Suk Ko, Min Goo Lee, Won Yu Kang, Shin Eun Lee, Soo Hyun Kim, Doo Sun Sim, Keun Ho Park, Nam Sik Yoon, Hyun Ju Youn, Kye Hun Kim, Hyun

Journal:

The American Journal of Cardiology

Year:

2009

Language:

english

File:

PDF, 32 KB

english, 2009

45

AS-125: Relation between Aortic Knob Calcification Observed by Simple Chest X-Ray or Fluoroscopy and Plaque Component Assessed by Virtual Histology-Intravascular Ultrasound

Young Joon Hong, Myung Ho Jeong, Yun Ha Choi, Jum Suk Ko, Min Goo Lee, Won Yu Kang, Shin Eun Lee, Soo Hyun Kim, Keun Ho Park, Doo Sun Sim, Nam Sik Yoon, Hyun Ju Yoon, Kye Hun Kim, Hyung Wook Park, Ju

Journal:

The American Journal of Cardiology

Year:

2009

Language:

english

File:

PDF, 31 KB

english, 2009

46

AS-275: Relation Between High-Sensitivity C-Reactive Protein and Coronary Plaque Components in Patients with Acute Coronary Syndrome: Virtual Histology–Intravascular Ultrasound Analysis

Young Joon Hong, Myung Ho Jeong, Yun Ha Choi, Jum Suk Ko, Min Goo Lee, Won Yu Kang, Shin Eun Lee, Soo Hyun Kim, Doo Sun Sim, Keun Ho Park, Nam Sik Yoon, Hyun Ju Youn, Kye Hun Kim, Hyung Wook Park, Ju

Journal:

The American Journal of Cardiology

Year:

2009

Language:

english

File:

PDF, 78 KB

english, 2009

47

AS-250: Usual Dose of Simvastatin Does Not Inhibit Plaque Progression and Lumen Loss at the Peri-Stent Reference Segments in Normocholesterolemic Patients Who Underwent Bare-Metal Stent Implantation: A Serial Intravascular Ultrasound Analysis

Young Joon Hong, Myung Ho Jeong, Jum Suk Ko, Min Goo Lee, Won Yu Kang, Shin Eun Lee, Soo Hyun Kim, Doo Sun Sim, Keun Ho Park, Nam Sik Yoon, Hyun Ju Youn, Kye Hun Kim, Hyung Wook Park, Ju Han Kim, Youn

Journal:

The American Journal of Cardiology

Year:

2009

Language:

english

File:

PDF, 31 KB

english, 2009

48

AS-274: Predictors of No-Reflow Phenomenon after Percutaneous Coronary Intervention in Patients with Acute Myocardial Infarction and Plaque Rupture

Young Joon Hong, Myung Ho Jeong, Yun Ha Choi, Jum Suk Ko, Min Goo Lee, Won Yu Kang, Shin Eun Lee, Soo Hyun Kim, Doo Sun Sim, Keun Ho Park, Nam Sik Yoon, Hyun Ju Youn, Kye Hun Kim, Hyung Wook Park, Ju

Journal:

The American Journal of Cardiology

Year:

2009

Language:

english

File:

PDF, 32 KB

english, 2009

49

Effect of Renal Function on Ultrasonic Coronary Plaque Characteristics in Patients With Acute Myocardial Infarction

Young Joon Hong, Myung Ho Jeong, Yun Ha Choi, Eun Hye Ma, Jum Suk Ko, Min Goo Lee, Keun Ho Park, Doo Sun Sim, Nam Sik Yoon, Hyun Ju Youn, Kye Hun Kim, Hyung Wook Park, Ju Han Kim, Youngkeun Ahn, Jeong

Journal:

The American Journal of Cardiology

Year:

2010

Language:

english

File:

PDF, 356 KB

english, 2010

50

AS-111: Sildenafil in Conjunction with an Angiotensin-Converting Enzyme Inhibitor Is Effective in Limiting Infarct

Doo Sun Sim, Myung Ho Jeong, Yun Hyeon Kim, Song Choi, Hyun Kuk Kim, Sung Soo Kim, Jum Suk Ko, Min Goo Lee, Keun Ho Park, Hyun Ju Yoon, Nam Sik Yoon, Kye Hun Kim, Young Joon Hong, Hyung Wook Park, Ju

Journal:

The American Journal of Cardiology

Year:

2010

Language:

english

File:

PDF, 47 KB

english, 2010